The latest episode of the Rostrum’s coronavirus series features James Shapiro, the Larry Miller professor of English and comparative literature at Columbia University, and a leading expert on Shakespeare. Shapiro has published widely on this subject, most recently Shakespeare in a Divided America. He is also an advisor to the Royal Shakespeare Company and to the Public Theater. We spoke with him about a major theme in Shakespeare’s work and life: disease. Specifically, pandemic plagues, which ravaged London repeatedly throughout Shakespeare’s career, shuttering the theaters, and which appear (obliquely and otherwise) in some of his greatest plays.